I04: Knowledge-based Multispectral Tissue Analysis

The aim of the project I04 "Knowledge-based Multispectral Tissue Analysis" is to create a computer-assisted quantification of tissue properties and risk factors that take into account different imaging techniques and longitudinal changes. The system aims at easing and objectifying the interpretation of different sources of information with respect to diagnosis, prognosis, therapy planning, and follow-up examination.

Project Leader

Dr. rer. nat.
Klaus H. Maier-Hein
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Our Team


Goetz M, Skornitzke S, Weber C, Fritz F, Mayer P, Koell M, Stiller W, und Maier-Hein K. 2016.

"Machine-learning based comparison of CT-perfusion maps and dual energy CT for pancreatic tumor detection“.

In Proceedings of SPIE Medical Imaging (accepted)

Goetz M, Heim E, Maerz K, Norajitra T, Hafezi M, Fard N, Mehrabi A, Knoll M, Weber C, Maier-Hein L, Maier-Hein KH.

“A learning-based, fully automatic liver tumor segmenta-tion pipeline based on sparsely annotated training data.”

In Proceedings of SPIE Medical Imaging, 2016 (accepted)

Goetz M, Weber C, Binczyk F, Polanska J, Tarnawski R, Bobek-Billewicz B, Koethe U, Kleesiek J, Stieltjes B, und Maier-Hein KH. 2015.

"DALSA: Domain Adaptation for Super-vised Learning from Sparsely Annotated MR Images.“

IEEE Transactions on Medical Imaging PP, (99)): 1–1.


Goetz M, Weber C, Stieltjes B, Maier-Hein K. 2014.

"Learning from Small Amounts of Labeled Data in a Brain Tumor Classification Task.“

Neural Information Processing Systems (NIPS).

Hauser T, Essig M, Jensen A, Laun FB, Münter M, Maier-Hein KH, und Stieltjes B. 2014.

"Prediction of Treatment Response in Head and Neck Carcinomas Using IVIM-DWI: Evaluation of Lymph Node Metastasis“.

European Journal of Radiology 83, (5): 783–87.


Maier-Hein KH, Brunner R, Lutz K, Henze R, Parzer P, Feigl N, Kramer J, Meinzer H-P, Resch F, und Stieltjes B. 2014.

"Disorder-Specific White Matter Alterations in Adolescent Borderline Personality Disorder.“

Biological Psychiatry 75, (1): 81–88.


Maier-Hein KH, Westin C-F, Shenton ME, Weiner MW, Raj A, Thomann P, Kikinis R, Stieltjes B, und Pasternak O. 2015.

"Widespread White Matter Degeneration Preceding the Onset of Dementia.“

Alzheimer’s & Dementia 11, (5): 485–93.e2.


Weber C, Goetz M, Stieltjes B, Polanska J, Binczyk F, Tarnawski R, Bobek-Billewicz B, und Maier-Hein K. 2014.

"Brain Tumor Progression Modeling - A Data Driven Approach“.

In Proceedings of MICCAI Workshop on Image-Guided Adaptive Radiation Therapy.

Gemmeke P, Maleshkova M, Philipp P, Götz M, Weber C, Kämpgen B, Nolden M, Maier-Hein K, and Rettinger A.

“Using Linked Data and Web APIs for Automating the Pre-Processing of Medical Images.”

In 5th Int. Workshop on Consuming Linked Data. Italy, 2014.

Philipp P, Gemmeke P, Maleshkova M, Götz M, Weber C, Kämpgen B, Nolden M, et al.

“Automatisierung von Vorverabeitungsschritten Für Medizinische Bilddaten Mit Semantischen Technologien.”

In Bildverarbeitung Für Die Medizin 2015. Springer Berlin Heidelberg, 2015.